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The levels of IL-10 is positively correlated with CRP amount (r = 0.41, P <

2016-05-01 View R&D Systems research products for IL-10. 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) Interleukin-10 is a protein in humans that is encoded by IL10 gene. Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by … IL-10 is an important regulator of the functions of lymphoid and myeloid cells. IL-10 can block the activation of cytokine synthesis and several accessory functions of macrophages. Human and mouse IL-10 share a 73% sequence homology. However, human IL-10 acts on both human and mouse target cells, while mouse IL-10 has species-specific activity.

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IL-10 is an anti-inflammatory cytokine.

Interleukin‐10 (IL‐10) is a key anti‐inflammatory cytokine. We aimed to assess IL‐10 and IL‐10 receptor (IL‐10R) expression in the gut, and determine whether these patterns are altered in patients with ulcerative colitis (UC).

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Conclusions and Unanswered Questions on IL-10. IL-10 is an anti-inflammatory cytokine that maintains the balance of the immune response, allowing the clearance of infection while minimizing damage to the host. IL-10 can also dampen the harmful immune responses elicited in autoimmunity and allergy.

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Interleukin 10 (IL-10 ili IL10), isto poznat kao ljudski inhibitorni faktor sinteze , je antiinflamatorni citokin. Kod ljudi IL-10 kodiran IL10 genom. Ovaj citokin proizvode prvenstveno monociti i u manjoj meri limfociti. Ovaj citokin ima pleiotropske efekte u imunoregulaciji i inflamaciji.

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Den anti-inflammatoriska effekten beror till stor del på att IL-10 nedreglerar MHC klass II uttryck på makrofager och dendritiska celler samt minskar IL-12

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